| Date | Location | Result | |
| 03/13/22 | Augusta, Ga. / Christenberry Fieldhouse | Augusta 82, UNC Pembroke 76 | Box score |
| 03/12/22 | Augusta, Ga. / Christenberry Fieldhouse | UNC Pembroke 74, Flagler 70 | Box score |
| 03/06/22 | Spartanburg, S.C. / Richardson Stadium | Belmont Abbey 79, UNC Pembroke 73 | Box score |
| 03/05/22 | Spartanburg, S.C. / Richardson Stadium | UNC Pembroke 67, Southern Wesleyan 66 | Box score |
| 02/24/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 101, North Greenville 71 | Box score |
| 02/22/22 | Wilson, N.C. / Wilson Gymnasium | UNC Pembroke 103, Barton 75 | Box score |
| 02/19/22 | Due West, S.C. / Belk Arena | UNC Pembroke 91, Erskine 72 | Box score |
| 02/16/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 101, Mount Olive 84 | Box score |
| 02/12/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 91, Belmont Abbey 75 | Box score |
| 02/11/22 | Pembroke, N.C. / Lumbee Bank Court | Southern Wesleyan 98, UNC Pembroke 88 | Box score |
| 02/05/22 | Banner Elk, N.C. / Williams Gymnasium | UNC Pembroke 100, Lees-McRae 83 | Box score |
| 02/04/22 | Bristol, Tenn. / Student Center Complex | UNC Pembroke 87, King 68 | Box score |
| 01/29/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 80, Emmanuel 59 | Box score |
| 01/26/22 | Florence, S.C. / Smith University Center | UNC Pembroke 76, Francis Marion 66 | Box score |
| 01/22/22 | Tigerville, S.C. / Hayes Gymnasium | UNC Pembroke 92, North Greenville 61 | Box score |
| 01/21/22 | Spartanburg, S.C. / Hannah Gymnasium | UNC Pembroke 95, Converse 55 | Box score |
| 01/17/22 | Mount Olive, N.C. / Kornegay Arena | UNC Pembroke 95, Mount Olive 66 | Box score |
| 01/13/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 97, Barton 90 | Box score |
| 01/08/22 | Central, S.C. / Tysinger Gymnasium | UNC Pembroke 90, Southern Wesleyan 86 | Box score |
| 01/06/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 84, Francis Marion 71 | Box score |
| 01/04/22 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 99, Chowan 79 | Box score |
| 12/18/21 | Belmont, N.C. / Wheeler Center | UNC Pembroke 71, Belmont Abbey 62 | Box score |
| 12/15/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 78, Converse 64 | Box score |
| 12/04/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 105, King 76 | Box score |
| 12/03/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 100, Lees-McRae 85 | Box score |
| 11/30/21 | Murfreesboro, N.C. / Bob Burke Court | UNC Pembroke 82, Chowan 63 | Box score |
| 11/23/21 | Royston, Ga. / Shaw Athletic Center | Emmanuel 82, UNC Pembroke 72 | Box score |
| 11/20/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 110, Erskine 73 | Box score |
| 11/17/21 | Pembroke, N.C. / Lumbee Bank Court | UNC Pembroke 77, Fayetteville St. 58 | Box score |
| 11/13/21 | Newberry, S.C. / Eleazer Arena | UNC Pembroke 92, Catawba 68 | Box score |
| 11/12/21 | Newberry, S.C. / Eleazer Arena | UNC Pembroke 85, Newberry 76 | Box score |